FAQ1: Which source are you using for the hyaluronidase ?
We are using pharmaceutical grade hyaluronidase that is sourced from bovine material.
FAQ2: What about the TSE/BSE threat in using materials from bovine sources ? Should we take extra precautions ?
The pharmaceutical grade hyaluronidase used in this product is derived from bovine testis and is certified with a TSE risk evaluation Certificate of Suitability (CEP).
The animals from which the hyaluronidase is derived, are determined “fit for human consumption” and originate from countries with “negligible BSE risk”, as determined Resolution “Recognition of the Bovine Spongiform Encephalopathy Risk Status of Member Countries”, adopted by the OIE.
According to the WHO guidelines on Tissue Infectivity Distribution in Transmissible Spongiform Encephalopathies (2010), testes from bovine source are classified as Category IC material (i.e. “Tissues with no detected infectivity”).
FAQ3: How long can denuded oocytes be stored?
Oocytes can be stored for maximum 6 hours after denudation. In general, oocytes are denuded 2-4 hours after oocyte retrieval. ICSI is performed 30 min after denudation.