Sil-Select Plus

Sperm preparation media

Sil-Select Plus is our home made new, improved and ready-to-use gradient system for semen preparation. The following gradients are available:

– Sil-Select Plus Upper layer (45%)
– Sil-Select Plus 80%
– Sil-Select Plus Lower layer (90%)

Sil-Select Plus gradients consist of silane-coated colloidal sicila particles suspended in HEPES-buffered Earle’s balanced salts solution, and as from batch FP18SIP20 supplemented with 0.4 – 2.2g/l human serum albumin.
Extensive testing during the design of the product has shown it to be non-cytotoxic and non-irritant with a non-significant allergenic potential.

Sil-Select Plus is produced from raw colloidal silica, so we have full control over each step in the production process. We have developed a very accurate purification system which results in a very clean product with endotoxin levels below 0.5EU/mL.

The Sil-Select Plus density gradient system (45%-90%) consists of a Sil-Select Plus Upper Layer (45%) and a Sil-Select Plus Lower Layer (90%).
We also offer Sil-Select Plus in an 80% dilution for use in IVF procedures.

Information about the composition of the products can be found in the material safety data sheet.

Regulatory

Europe: CE-marked – Canada: Health Canada License – Brazil: registered

Product order codes

SIP008 : Sil-Select Plus – 8 preparations
SIP016 : Sil-Select-Plus – 16 preparations
SIP050 : Sil-Select Plus – 2 x 50mL
SIP100 : Sil-Select Plus – 2 x 100mL
SIP80_100 : Sil-Select Plus 80% – 100mL

pH 7.2 – 7.9 (7.2-7.6 at release)
Osmolality 280-310mOsm/kg (Upper Layer)
290-330mOsm/kg (Lower Layer)
290-330mOsm/kg (80%)
Sterility Sterile
Endotoxine < 0.5 EU/mL
Sperm Survival test ≥ 80% survival after 4 hours exposure of density selected spermatozoa to the test medium; and ≥ 75% survival after 24 hours exposure of density selected spermatozoa to the test medium
Density 1.1050-1.1150g/mL (Lower Layer)
1.097-1.107g/mL (80%)
Viscosity in cP (25°C) <1.65cP (Lower Layer, 80%)
Albumin FDA (USA) and EMA (Europe) compliant
Shelflife 18 months from date of produce

Sperm ProcessingInsemination

Ready-to-use density gradients for sperm selection in human assisted reproduction procedures

Instructions For Use
Material Safety Data Sheet