SpermMar Test IgA

Test for the detection of anti-sperm antibodies

SpermMar Test IgA and SpermMar Test IgG are rapid, easy-to-use tests for the detection of anti-sperm antibodies in semen and serum.

Anti sperm antibodies (ASA) are produced when the blood-testis barrier is disrupted by obstruction, infection or traumatism. Immunoglobulines of the IgG class are usually present in both serum and semen, and the IgG antibodies attach to the spermatozoa. ASA of the IgA class are secreted by the accessory sex glands and are found in semen only. ASA of the IgG class may be detected in seminal plasma, but there is usually no free IgA in seminal plasma. Anti sperm antibodies of the IgA class almost never occur without IgG antibodies.

When more than 40% of motile spermatozoa present ASA of the IgG class, complementary testing for IgA antibodies is advisable

The immunological factor reduces the probability of spontaneous conception, and this is particularly true when ASA of the IgA class are also present.

SpermMar Test IgA has a 12 month shelf life from production date. Information about the composition of the product can be found in the material safety data sheet.

Regulatory information

Europe: CE-marked – USA: registered – Canada: Health Canada licence
Brazil: registered – Australia: registered

Product order codes

SPMA_S : SpermMar Test IgA – Single kit – 50 tests
SPMA_C : SpermMar Test IgA – Complete kit – 50 tests

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Hussein T.M., Elneily D., Eid A.A., Abou-ElKhier H., Assessment of antisperm antibodies in a sample of Egyptian patients with hepatitis C virus infection, Andrologia (2017),Vol.49,No.e12664

Laudat A., Burc-Struxiano L., Is Absence of Spontaneous Agglutinates of Spermatozoa in Semen a Reliable Indicator of Non-Autosensization against Human Sperm Antigens?, Open Access Library Journal (2016),Vol.3,No.e2978

Marconi M., Nowotny A., Pantke P., et al., Antisperm antibodies detected by mixed agglutination reaction and immunobead test are not associated with chronic inflammation and infection of the seminal tract, Andrologia (2008),Vol.40,pp.227-234

Marconi M., Pilatz A., Wagenlehner F., et al., Are Antisperm Antibodies Really Associated with Proven Chronic Inflammatory and Infectious Diseases of the Male Reproductive Tract?, European Urology (2009),Vol.56,pp.708-715

Ombelet W., Vandeput H., Janssen M., et al., Treatment of male infertility due to sperm surface antibodies: IUI or IVF?, Human Reproduction (1997),Vol.12,No.6,pp.1165-1170

Poppe K., Glinoer D., Tournaye H., et al., Is systematic screening for thyroid disorders indicated in subfertile men?, European Journal of Endocrinology (2006),Vol.154,pp.363-366

Tennakoon V., Weerasekera DS., Yasawardene SG., Successful pregnancy outcomes following in-vitro fertilization in infertile couples with high levels of antisperm antibodies, Sri Lanka Journal of Obstetrics and Gynaecology (2010),Vol.32,pp.47-48

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When more than 40% of motile spermatozoa present ASA of the IgG class, complementary testing for IgA antibodies is advisable

Instructions For Use

Material Safety Data Sheet