HOS Test

Sperm vitality test

The hypo-osmotic swelling test is a sperm vitality test based on the principle that live spermatozoa swell due to the absorption of a hypo-osmotic solution. The HOS test is based on the test procedure described in the WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction (1999).

The HOS Test has a shelf life of 12 months from production date. Information about the composition of the product can be found in the material safety data sheet.

The hypo-osmotic swelling test has been CE marked according to the specifications set forth in the European in vitro diagnostic medical device regulation (EU) 2017/746 (IVDR).


Europe: CE-marked (IVDR, Notified Body number 2797)
Canada: Health Canada License – USA: registered
Brazil: registered – Australia: registered

Product order codes

HOST : Hypo-osmotic Swelling test – 5x 20mL

Micinski P., Pawlicki K., Wielgus E., et al., Total reactive antioxidant potential and DNA fragmentation index as fertility sperm parameters, Reproductive Biology (2011),Vol.11,No.2,pp.135-44

The HOS Test is a microscopic, diagnostic test to facilitate the estimation of sperm vitality

Instructions For Use
Material Safety Data Sheet